The P40401-B21 is a HPE cpus & processors component with capacity 64 GB, clock speed 2.2 GHz, power 800W. Pro Disk Network sells the P40401-B21 for $4,350.40 with same-day US shipping and a 30-day return guarantee.
Reviewed By
Reviewed by:Pro Disk Network Engineering Team — . Specifications, compatibility, and pricing for the P40401-B21 are shown on this page.
Trust Signals
US-based LLC — 7345 W Sand Lake Rd, STE 210, Office 3208, Orlando, FL 32819
Same-Day US Shipping — orders before 3pm ET ship today via UPS
30-Day Returns — pre-paid label on DOA and defective items
Quick Answer: What socket does the P40401-B21 use?
Confirm the socket against your motherboard's CPU support list - Intel Xeon Scalable spans LGA 3647 (1st/2nd gen), LGA 4189 (3rd gen Ice Lake), and LGA 4677 (4th/5th gen Sapphire/Emerald Rapids). A BIOS update is often required for newer steppings even on the same socket. Email sales@prodisknetwork.com with your motherboard model for a compatibility check.
How fast does the P40401-B21 ship?
Pro Disk Network dispatches the P40401-B21 same-day on orders confirmed before 3 pm ET. Multi-pallet projects requiring crating ship within 2 business days. International shipping (Canada, Mexico, EU, APAC) takes 3-7 business days via DHL Express or FedEx International Priority.
The P40401-B21 is deployed by US enterprises, MSPs, government, and education customers across multiple infrastructure scenarios. Below are the most common deployment patterns Pro Disk Network sees in real-world orders.
Citrix VDI Pool — Frequency-sensitive — prefer high-clock 16–18 core SKUs over high-core-count parts to maintain user-perceived snappiness.
Kubernetes / Tanzu Workers — Higher core count amortises better across many small Pods. EVC mode planning matters for live-migrate parity.
AI Inference Host — Sapphire Rapids and Emerald Rapids include AMX silicon for INT8 inference acceleration — meaningful uplift for BERT, ResNet, and LLM serving.
What is the P40401-B21?
The P40401-B21 is a HPE server-class processor with capacity 64 GB and clock speed 2.2 GHz, manufactured by HPE. Pro Disk Network ships this part new and certified-refurbished from our US warehouse with same-day dispatch on orders placed before 3 PM ET, backed by a 30-day return guarantee.
Pros & Cons of P40401-B21
Pros
Same-day shipping from our US warehouse cuts deployment lead time
Cons
Older socket family — confirm motherboard compatibility
BIOS update typically required for newer CPU steppings
Not a fit for desktop platforms — these are server SKUs
Frequently Asked Questions about P40401-B21
Is the P40401-B21 a genuine HPE part?
Yes. Pro Disk Network sources every P40401-B21 as factory-original HPE inventory. New units arrive sealed in OEM packaging; refurbished units are pulled from decommissioned HPE servers, surface-tested, and re-warranted by Pro Disk Network for 90 days.
What socket does the P40401-B21 use?
Confirm the socket against your motherboard's CPU support list - Intel Xeon Scalable spans LGA 3647 (1st/2nd gen), LGA 4189 (3rd gen Ice Lake), and LGA 4677 (4th/5th gen Sapphire/Emerald Rapids). A BIOS update is often required for newer steppings even on the same socket. Email sales@prodisknetwork.com with your motherboard model for a compatibility check.
How fast does the P40401-B21 ship?
Pro Disk Network dispatches the P40401-B21 same-day on orders confirmed before 3 pm ET. Multi-pallet projects requiring crating ship within 2 business days. International shipping (Canada, Mexico, EU, APAC) takes 3-7 business days via DHL Express or FedEx International Priority.
What is the warranty on the P40401-B21?
New P40401-B21 units carry the full HPE manufacturer warranty (typically 1 to 5 years depending on product line). Refurbished and bulk-OEM units include a Pro Disk Network advance-replacement warranty (90 days refurbished). DOA replacement is free within 30 days of receipt.
Do you offer bulk pricing for the P40401-B21?
Email sales@prodisknetwork.com with the quantity and target ship date for a quote within one business day.
Socket Compatibility, EVC Mode, and BIOS Revision Planning
For Hyper-V clusters, Live Migration compatibility is more forgiving but still benefits from matched CPU stepping across cluster nodes. For Kubernetes / Tanzu, CPU heterogeneity is acceptable because pods are stateless, but resource-request planning becomes harder when nodes have different core counts.
AI Workloads, AMX, and the Inference Performance Story
Late-generation Intel Xeon processors (Sapphire Rapids, Emerald Rapids, Granite Rapids) include AMX (Advanced Matrix Extensions) silicon that accelerates INT8 inference workloads dramatically. For the P40401-B21, if AMX is present, BERT-base inference throughput improves 4-6× over the previous generation; LLM inference (Llama 2 7B INT8 quantised) improves 2-3×. AMX does not require code changes when used through libraries that already support it (oneAPI, ONNX Runtime, OpenVINO).