HPE P08257-B21 InfiniBand MCX653106A-ECAT HDR100 2-Ports 100GbE Qsfp56 PCI Express 3.0 x16 Ethernet Network Adapter for ProLiant Server. In Stock Brand: HPE Part Number: P08257-B21 Category: NIC Key Specs: 2-Port, 100GbE Availability: In Stock Shipping: Fast US-based shipping Order the HPE P08257-B21 today from ProDisk Network — your trusted source for enterprise IT hardware.
The P08257-B21 is a HPE network adapters component with interface PCI Express, network speed 100 GbE. Pricing on the P08257-B21 is quote-based — email sales@prodisknetwork.com or use our live chat for a quote within one business day.
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Reviewed by:Pro Disk Network Engineering Team — . Specifications, compatibility, and pricing for the P08257-B21 are shown on this page.
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Quick Answer: Is the P08257-B21 compatible with my switch?
Pro Disk Network validates every P08257-B21 against the target switch's published compatibility matrix before shipment. If you let us know your switch model and firmware version, we will confirm fitment and code the module appropriately (Cisco-coded, Juniper-coded, HPE-coded, etc.) at no extra charge.
How fast does the P08257-B21 ship?
If in stock, the P08257-B21 ships same business day on US orders placed before 3 pm ET. Most US ZIP codes receive next-business-day or 2-day delivery via FedEx/UPS Ground or Express. Bulk and project orders shipping in pallets are typically dispatched within 24-48 hours.
The P08257-B21 is deployed by US enterprises, MSPs, government, and education customers across multiple infrastructure scenarios. Below are the most common deployment patterns Pro Disk Network sees in real-world orders.
Spine-Leaf Fabric — Top-of-rack 25G/100G aggregation between leaf and spine switches. Match speed and form factor across both endpoints.
Server Uplink — 10G/25G server-to-leaf uplink — pair with matching DAC or AOC at the host NIC to avoid optic mismatch.
DCI (Data Center Interconnect) — Inter-DC routing or aggregation. LR4/LR8 transceivers for 10–80 km, ER4 for 40 km, ZR4 for coherent long-haul.
Campus Distribution — Catalyst-class campus distribution between IDF and MDF closets. PoE+ where wireless APs and IP phones share infrastructure.
What is the P08257-B21?
The P08257-B21 is a HPE enterprise networking device with interface PCI Express and network speed 100 GbE, manufactured by HPE. Pro Disk Network ships this part new and certified-refurbished from our US warehouse with same-day dispatch on orders placed before 3 PM ET, backed by a 30-day return guarantee.
Pros & Cons of P08257-B21
Pros
Matched-pair option for redundant link orders
Cabling and DAC/AOC labels clearly mark optic class
Cons
Not for hyperscale ZR coherent — different SKU family
Some vendors deprecate firmware on EOL part numbers
Mismatched optic+switch firmware can require manual override
Frequently Asked Questions about P08257-B21
Is the P08257-B21 a genuine HPE part?
Yes. Pro Disk Network sources every P08257-B21 as factory-original HPE inventory. New units arrive sealed in OEM packaging; refurbished units are pulled from decommissioned HPE servers, surface-tested, and re-warranted by Pro Disk Network for 90 days.
Is the P08257-B21 compatible with my switch?
Pro Disk Network validates every P08257-B21 against the target switch's published compatibility matrix before shipment. If you let us know your switch model and firmware version, we will confirm fitment and code the module appropriately (Cisco-coded, Juniper-coded, HPE-coded, etc.) at no extra charge.
How fast does the P08257-B21 ship?
If in stock, the P08257-B21 ships same business day on US orders placed before 3 pm ET. Most US ZIP codes receive next-business-day or 2-day delivery via FedEx/UPS Ground or Express. Bulk and project orders shipping in pallets are typically dispatched within 24-48 hours.
What is the warranty on the P08257-B21?
New P08257-B21 units carry the full HPE manufacturer warranty (typically 1 to 5 years depending on product line). Refurbished and bulk-OEM units include a Pro Disk Network advance-replacement warranty (90 days refurbished). DOA replacement is free within 30 days of receipt.
Do you offer bulk pricing for the P08257-B21?
Email sales@prodisknetwork.com with the quantity and target ship date for a quote within one business day.
Optic Coding, Vendor Lock-In, and Multi-Vendor Compatibility
Networking optics — SFP, SFP+, QSFP+, QSFP28 — are physically interoperable across vendors but logically restricted by firmware coding. The P08257-B21 is coded for a specific vendor family at our factory step before shipping, which preserves the OEM warranty workflow and allows the optic to be recognised without ‘service unsupported-transceiver’ CLI overrides. Mixing third-party optics with same-vendor optics in the same chassis is safe; mixing across vendor codings sometimes triggers warnings in the switch log.
Bandwidth Sizing for Spine-Leaf, EVPN-VXLAN, and Hyperconverged Storage
For EVPN-VXLAN overlays, the P08257-B21 carries the underlay tunnels in addition to the workload traffic. Plan for VXLAN encapsulation overhead (50 bytes) plus MTU headroom; set the underlay MTU to 9216 (jumbo frames) and the overlay MTU to 9000. Make sure both the P08257-B21 and the connected NICs support jumbo frames — some older NICs cap at 9000-byte payloads even when jumbo-enabled.