Sourced for enterprise IT teams, the Dell 341-6643 (341-6643 - Dell 750GB 7200RPM SATA 3GB/s 16MB Cache 3.5-inch Hard Disk Drive) is a Desktop Hard Drive component appropriate for new-build, expansion, or warranty-replacement procurement. Technical specifications include spindle speed of 7,200 RPM, form factor of 3.5-inch, interface of SATA, data rate of 3 Gb/s, cache of 16MB. Appropriate for OS boot tier (Windows Server, RHEL, Ubuntu Server, ESXi), application data tier, database log volumes, and tier-2 capacity in mixed-storage clusters. Pro Disk Network supplies the 341-6643 to US business buyers. Stocked units ship same-day on in-stock orders placed before 3pm ET. Pro Disk Network applies a 90-day functional warranty. Free US ground shipping on orders over $150; same-day expedited (UPS Next Day Air, FedEx Priority) available at checkout.
The 341-6643 is a Dell desktop hard drive component with spindle speed 7,200 RPM, form factor 3.5-inch, interface SATA. Pro Disk Network sells the 341-6643 for $155.80 with same-day US shipping and a 30-day return guarantee.
Reviewed By
Reviewed by:Pro Disk Network Engineering Team — . Specifications, compatibility, and pricing for the 341-6643 are shown on this page.
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Same-Day US Shipping — orders before 3pm ET ship today via UPS
30-Day Returns — pre-paid label on DOA and defective items
Quick Answer: Will the 341-6643 work with my RAID controller?
The 341-6643 operates with any standard SAS/SATA/NVMe-compatible RAID controller (Dell PERC, HPE Smart Array, LSI/Broadcom MegaRAID, Adaptec, IBM ServeRAID, Lenovo ThinkSystem RAID). Mixing this drive in the same RAID volume with drives of different speed/capacity is supported but never recommended.
How fast does the 341-6643 ship?
If in stock, the 341-6643 ships same business day on US orders placed before 3 pm ET. Most US ZIP codes receive next-business-day or 2-day delivery via FedEx/UPS Ground or Express. Bulk and project orders shipping in pallets are typically dispatched within 24-48 hours.
The 341-6643 is deployed by US enterprises, MSPs, government, and education customers across multiple infrastructure scenarios. Below are the most common deployment patterns Pro Disk Network sees in real-world orders.
VMware vSAN Capacity Tier — Used as bulk storage in all-flash and hybrid vSAN clusters. Pair with NVMe cache-tier drives for SLA-grade write throughput at half the cost of all-NVMe.
Veeam Backup Repository — Cost-optimised backup target for Veeam B&R, Rubrik, or Cohesity primary backup tier. RAID 6 over 8–24 drives delivers 100+ TB usable per server.
Splunk Warm/Cold Tier — Appropriate for Splunk warm/cold/frozen indexes where ingest write rates are below 200 MB/s per node. Avoid for hot-tier indexes — use NVMe instead.
File Server / SMB Shares — General-purpose Windows Server / Samba shares for departmental file storage. RAID 5 for capacity, RAID 10 for IOPS-sensitive workloads.
What is the 341-6643?
The 341-6643 is a Dell enterprise-grade hard drive with spindle speed 7,200 RPM and form factor 3.5-inch, manufactured by Dell. Pro Disk Network ships this part new and certified-refurbished from our US warehouse with same-day dispatch on orders placed before 3 PM ET, backed by a 30-day return guarantee.
Pros & Cons of 341-6643
Pros
Same-day US shipping from our US warehouse
Cons
Refurbished tier reseals — original retail box not included
Single-drive purchases ship in static-shield bags, not retail packaging
Lead time on 24+ drive orders may extend 2–4 business days
Frequently Asked Questions about 341-6643
Is the 341-6643 a genuine Dell part?
Yes. Pro Disk Network sources every 341-6643 as factory-original Dell inventory. New units arrive sealed in OEM packaging; refurbished units are pulled from decommissioned Dell servers, surface-tested, and re-warranted by Pro Disk Network for 90 days.
Will the 341-6643 work with my RAID controller?
The 341-6643 operates with any standard SAS/SATA/NVMe-compatible RAID controller (Dell PERC, HPE Smart Array, LSI/Broadcom MegaRAID, Adaptec, IBM ServeRAID, Lenovo ThinkSystem RAID). Mixing this drive in the same RAID volume with drives of different speed/capacity is supported but never recommended.
How fast does the 341-6643 ship?
If in stock, the 341-6643 ships same business day on US orders placed before 3 pm ET. Most US ZIP codes receive next-business-day or 2-day delivery via FedEx/UPS Ground or Express. Bulk and project orders shipping in pallets are typically dispatched within 24-48 hours.
What is the warranty on the 341-6643?
New 341-6643 units carry the full Dell manufacturer warranty (typically 1 to 5 years depending on product line). Refurbished and bulk-OEM units include a Pro Disk Network advance-replacement warranty (90 days refurbished). DOA replacement is free within 30 days of receipt.
Do you offer bulk pricing for the 341-6643?
Email sales@prodisknetwork.com with the quantity and target ship date for a quote within one business day.
Other parts that share the 341 series prefix — useful when sourcing matched lots, hot-spare pools, or capacity-tier expansions.
341-6608 — 341-6608 - Dell 320GB 5400RPM SATA 2.5-inch Hard Disk Drive — $251.78
341-6610 — 341-6610 - Dell 146GB 15000RPM SAS Hard Disk Drive — $279.11
341-6611 — 341-6611 - Dell 300GB 15000RPM SAS 3GB/s 3.5-inch Low Profile (1.0inch) Hard Drive with Tray for PowerEdge and POWERV — $259.50
341-6612 — 341-6612 - Dell 400GB 10000RPM SAS 3.5-inch Internal Hard Disk Drive — $431.84
341-6616 — 341-6616 - Dell 160GB 5400RPM SATA 2.5-inch Hard Disk Drive — $221.68
341-6617 — 341-6617 - Dell 160GB 7200RPM SATA 3.5-inch Hard Disk Drive — $210.14
341-6618 — 341-6618 - Dell 250GB 5400RPM SATA 2.5-inch Hard Disk Drive — $226.72
341-6619 — 341-6619 - Dell 320GB 5400RPM SATA 2.5-inch Hard Disk Drive — $251.78
341-6639 — 341-6639 - Dell 80GB 7200RPM SATA 3GB/s 8MB Cache 3.5-inch Hard Disk Drive — $136.03
341-6640 — 341-6640 - Dell 160GB 7200RPM SATA 1.5GB/s 8MB Cache 3.5-inch Hard Disk Drive — $199.51
341-6641 — 341-6641 - Dell 250GB 7200RPM SATA 3GB/s 8MB Cache 3.5-inch Hard Disk Drive — $240.78
341-6642 — 341-6642 - Dell 320GB 7200RPM SATA 3GB/s 16MB Cache 3.5IN Low Profile (1.0inch) Internal Hard Drive FOR — $267.16
Pro Disk Network Buyer’s Guide: Desktop Hard Drive
How to Pick the Right Drive Capacity for Your Use Case
Sizing a storage drive correctly is the difference between a system that runs predictably for five years and one that you replace under emergency conditions at 18 months. For the 341-6643, plan capacity around three numbers: working-set size, retention window, and overhead headroom. Working set is the actively-read data — databases, indexes, hot files. Retention window is how long you keep cold data online before tiering off. Overhead headroom should be 25-30%: drives run noticeably slower above 80% utilisation and metadata operations stall above 90%.
Drive Health Monitoring: SMART, Workload Rating, and Predictive Failure
Workload rating — expressed as TB written per year — matters more than raw capacity in choosing the 341-6643 for sustained-write workloads. Consumer SATA drives are rated for 55 TB/year; enterprise SATA for 180-550 TB/year; enterprise SAS for 550 TB+/year; mixed-use NVMe for 1-3 PB/year over five years. Match the rating to your sustained write profile, then add 30% headroom.