Replacement for P25961-B21: Drop-In Alternatives We Stock
Looking for a replacement for the P25961-B21 (HPE P25961-B21 Ethernet MCX623106AS-CDAT 100GbE QSFP28 PCI Express 4.0 x16 Network Adapter)? Pro Disk Network ships HP drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the P25961-B21
| SKU | P25961-B21 |
|---|---|
| Product | HPE P25961-B21 Ethernet MCX623106AS-CDAT 100GbE QSFP28 PCI Express 4.0 x16 Network Adapter |
| Current price | $1,910.53 |
| Stock status | In Stock |
| Detail page | View P25961-B21 › |
Drop-in replacements for P25961-B21
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
NC552SFP - HP 10GB 2-Port Ethernet Server Adapter Network Adapter PCI-Express 2.0 X8 10 Gigabit Ethernet 2 Ports
SKU: NC552SFP
Price: $61.05
614202-B21 - HP Nc552SFP 10GB 2-Port Ethernet Server Adapter Network Adapter PCI-Express 2.0 X8 10 Gigabit Ethernet 2 Ports
SKU: 614202-B21
Price: $280.87
HPE P08355-001 InfiniBand HDR100/Ethernet 2-Ports 100GbEPCI-Express 3.0 x16 Low-Profile Gigabit Ethernet Network Adapter
SKU: P08355-001
Price: $549.47
HPE 725052-B21 2-Ports 10Gb/s RJ-45 Gigabit Ethernet PCI Express 2.1 x8 Network Adapter Card
SKU: 725052-B21
Price: $82.11
HPE 869570-001 HP 869570-001 2 x Ports 25GBase-X PCI Express 3.0 x8 Ethernet Network Adapter
SKU: 869570-001
Price: $89.47
HPE P22703-B21 Ethernet 2-Ports 25GbE SFP28 PCI Express 3.0 Network Adapter for ProLiant Server
SKU: P22703-B21
Price: $117.89
HPE 669280-001 4-Ports 1Gb/s 10/100/1000Base-T PCI-Express x4 366FLR FIO Gigabit Ethernet Network Adapter
SKU: 669280-001
Price: $128.42
HPE 665240-B21 4-Ports 1Gb/s 10/100/1000Base-T PCI-Express x4 366FLR FIO Gigabit Ethernet Network Adapter
SKU: 665240-B21
Price: $128.42
HPE P22199-001 HP P22199-001 Marvell QL41132HLCU 2-Ports Sfp+ 10GbE PCI Express 3.0 x8 Ethernet Network Adapter for ProLiant Server
SKU: P22199-001
Price: $138.95
HPE P21935-001 HP P21935-001 Marvell QL41132HLCU 2-Ports Sfp+ 10GbE PCI Express 3.0 x8 Ethernet Network Adapter for ProLiant Server
SKU: P21935-001
Price: $138.95
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.