Replacement for 450291-B21: Drop-In Alternatives We Stock
Looking for a replacement for the 450291-B21 (HP 450291-B21 ProLiant ML150 Gen 5 Hot Plug SAS/SATA Configure-To-Order Server. In Stock)? Pro Disk Network ships HP drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the 450291-B21
| SKU | 450291-B21 |
|---|---|
| Product | HP 450291-B21 ProLiant ML150 Gen 5 Hot Plug SAS/SATA Configure-To-Order Server. In Stock |
| Stock status | In Stock |
| Detail page | View 450291-B21 › |
Drop-in replacements for 450291-B21
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
722315-B21 - HP ProLiant DL320E Gen8 V2 Hot-Plug 4-SFF Configure-to-Order Server
SKU: 722315-B21
Price: $629.47
722314-B21 - HP ProLiant DL320e Gen8 V2 Hot Plug 2 LFF Configure-to-order Server
SKU: 722314-B21
Price: $684.21
872305-B21 - HP ProLiant ML110 Gen10 4LFF Non-Hot Plug Configure-to-Order Server
SKU: 872305-B21
Price: $1,647.37
740897-B21 - HP ProLiant ML350e Gen8 v2 Hot Plug 8 SFF Configure-to-order Server
SKU: 740897-B21
Price: $1,784.39
740896-B21 - HP ProLiant ML350e Gen8 v2 Hot Plug 4 LFF Configure-to-order Server
SKU: 740896-B21
Price: $1,853.92
HPE P25447-001 ProLiant XL225n Gen 10 Plus 1U Node Configure-to-Order Server
SKU: P25447-001
Price: $278.95
722447-B21 - HP ProLiant ML310E G8 V2 Hot-Pluggable Configure-to-Order Server
SKU: 722447-B21
Price: $694.74
HPE P05172-B21 ProLiant DL380 Gen10 Plus 8-Bays Hot-Swap 2.5" SFF 32x DDR4 DIMM Rack-mountable Configure to Order Server
SKU: P05172-B21
Price: $3,994.74
410006-B21 - HP ProLiant ML570 G4 SAS Configure-to-Order Tower Chassis
SKU: 410006-B21
Price: $6,244.21
374295-405 - HP ProLiant DL320 G3 SATA Configure-to-Order Server System
SKU: 374295-405
Price: $515.79
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.