This Cisco WS-C4503-E-S2-48V delivers Switch Modules functionality and is built for 24/7 enterprise duty cycles. Technical specifications include voltage of 48V. Workload fit covers VMware NSX overlay networking, Kubernetes pod-to-pod east-west bandwidth, Storage Replica replication, and high-throughput backup network paths between ToR switches and backup targets. Pro Disk Network maintains the WS-C4503-E-S2-48V in our enterprise inventory and verifies each unit against manufacturer datasheet specifications prior to listing. New stock ships factory-sealed where available; refurbished units are tested under load before dispatch and ship with a 90-day Pro Disk Network functional warranty. Same-day dispatch on in-stock orders placed before 3pm ET; free standard ground shipping on US orders over $150.
The WS-C4503-E-S2-48V is a Cisco switch modules component with voltage 48V. Pricing on the WS-C4503-E-S2-48V is quote-based — email sales@prodisknetwork.com or use our live chat for a quote within one business day.
Reviewed By
Reviewed by:Pro Disk Network Engineering Team — . Specifications, compatibility, and pricing for the WS-C4503-E-S2-48V are shown on this page.
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Same-Day US Shipping — orders before 3pm ET ship today via UPS
30-Day Returns — pre-paid label on DOA and defective items
Quick Answer: Is the WS-C4503-E-S2-48V compatible with my switch?
Pro Disk Network validates every WS-C4503-E-S2-48V against the target switch's published compatibility matrix before shipment. If you let us know your switch model and firmware version, we will confirm fitment and code the module appropriately (Cisco-coded, Juniper-coded, HPE-coded, etc.) at no extra charge.
How fast does the WS-C4503-E-S2-48V ship?
If in stock, the WS-C4503-E-S2-48V ships same business day on US orders placed before 3 pm ET. Most US ZIP codes receive next-business-day or 2-day delivery via FedEx/UPS Ground or Express. Bulk and project orders shipping in pallets are typically dispatched within 24-48 hours.
The WS-C4503-E-S2-48V is deployed by US enterprises, MSPs, government, and education customers across multiple infrastructure scenarios. Below are the most common deployment patterns Pro Disk Network sees in real-world orders.
Spine-Leaf Fabric — Top-of-rack 25G/100G aggregation between leaf and spine switches. Match speed and form factor across both endpoints.
Server Uplink — 10G/25G server-to-leaf uplink — pair with matching DAC or AOC at the host NIC to avoid optic mismatch.
DCI (Data Center Interconnect) — Inter-DC routing or aggregation. LR4/LR8 transceivers for 10–80 km, ER4 for 40 km, ZR4 for coherent long-haul.
Campus Distribution — Catalyst-class campus distribution between IDF and MDF closets. PoE+ where wireless APs and IP phones share infrastructure.
What is the WS-C4503-E-S2-48V?
The WS-C4503-E-S2-48V is a Cisco enterprise networking device with voltage 48V, manufactured by Cisco. Pro Disk Network ships this part new and certified-refurbished from our US warehouse with same-day dispatch on orders placed before 3 PM ET, backed by a 30-day return guarantee.
Pros & Cons of WS-C4503-E-S2-48V
Pros
Matched-pair option for redundant link orders
Cabling and DAC/AOC labels clearly mark optic class
Cons
Third-party optic — some firmware revs require "service unsupported transceiver-type"
Bulk DAC orders may ship LTL on >100-pc reels
Confirm transceiver coding before mixing vendors in the same chassis
Frequently Asked Questions about WS-C4503-E-S2-48V
Is the WS-C4503-E-S2-48V a genuine Cisco part?
Yes. Pro Disk Network sources every WS-C4503-E-S2-48V as factory-original Cisco inventory. New units arrive sealed in OEM packaging; refurbished units are pulled from decommissioned Cisco servers, surface-tested, and re-warranted by Pro Disk Network for 90 days.
Is the WS-C4503-E-S2-48V compatible with my switch?
Pro Disk Network validates every WS-C4503-E-S2-48V against the target switch's published compatibility matrix before shipment. If you let us know your switch model and firmware version, we will confirm fitment and code the module appropriately (Cisco-coded, Juniper-coded, HPE-coded, etc.) at no extra charge.
How fast does the WS-C4503-E-S2-48V ship?
If in stock, the WS-C4503-E-S2-48V ships same business day on US orders placed before 3 pm ET. Most US ZIP codes receive next-business-day or 2-day delivery via FedEx/UPS Ground or Express. Bulk and project orders shipping in pallets are typically dispatched within 24-48 hours.
What is the warranty on the WS-C4503-E-S2-48V?
New WS-C4503-E-S2-48V units carry the full Cisco manufacturer warranty (typically 1 to 5 years depending on product line). Refurbished and bulk-OEM units include a Pro Disk Network advance-replacement warranty (90 days refurbished). DOA replacement is free within 30 days of receipt.
Do you offer bulk pricing for the WS-C4503-E-S2-48V?
Email sales@prodisknetwork.com with the quantity and target ship date for a quote within one business day.
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Pro Disk Network Buyer’s Guide: Switch Modules
Optic Coding, Vendor Lock-In, and Multi-Vendor Compatibility
Networking optics — SFP, SFP+, QSFP+, QSFP28 — are physically interoperable across vendors but logically restricted by firmware coding. The WS-C4503-E-S2-48V is coded for a specific vendor family at our factory step before shipping, which preserves the OEM warranty workflow and allows the optic to be recognised without ‘service unsupported-transceiver’ CLI overrides. Mixing third-party optics with same-vendor optics in the same chassis is safe; mixing across vendor codings sometimes triggers warnings in the switch log.
Bandwidth Sizing for Spine-Leaf, EVPN-VXLAN, and Hyperconverged Storage
For EVPN-VXLAN overlays, the WS-C4503-E-S2-48V carries the underlay tunnels in addition to the workload traffic. Plan for VXLAN encapsulation overhead (50 bytes) plus MTU headroom; set the underlay MTU to 9216 (jumbo frames) and the overlay MTU to 9000. Make sure both the WS-C4503-E-S2-48V and the connected NICs support jumbo frames — some older NICs cap at 9000-byte payloads even when jumbo-enabled.