Replacement for 21227-00-50G: Drop-In Alternatives We Stock
Looking for a replacement for the 21227-00-50G (21227-00-50G - Sapphire Radeon R9 290 4GB GDDR5 2DVI/ HDMI/ DisplayPort PCI Express Video Graphics Card)? Pro Disk Network ships drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the 21227-00-50G
| SKU | 21227-00-50G |
|---|---|
| Product | 21227-00-50G - Sapphire Radeon R9 290 4GB GDDR5 2DVI/ HDMI/ DisplayPort PCI Express Video Graphics Card |
| Current price | $723.18 |
| Stock status | In Stock |
| Detail page | View 21227-00-50G › |
Drop-in replacements for 21227-00-50G
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
100362SR - Sapphire Radeon R9 290 4GB GDDR5 PCI Express 3.0 x16 DVI/ HDMI/ DisplayPort Video Graphics Card
SKU: 100362SR
Price: $836.51
90YV05F0-M0NA00 - ASUS AMD Radeon R9 290 4GB GDDR5 512-Bit HDMI / DisplayPort / DVI PCI Express 3.0 Video Graphics Card
SKU: 90YV05F0-M0NA00
Price: $639.43
MCP-290-00059-0B Supermicro MCP-290-00059-0B 4U Rackmount Rail Kit
SKU: MCP-290-00059-0B
Price: $176.84
21226-00-40G - Sapphire Radeon R9 290X 4GB GDDR5 2DVI/ HDMI/ DisplayPort PCI Express Video Graphics Card
SKU: 21226-00-40G
Price: $828.86
100361SR - Sapphire Radeon R9 290X 4GB GDDR5 PCI Express 3.0 x16 DVI/ HDMI/ DisplayPort Video Graphics Card
SKU: 100361SR
Price: $977.88
11256-00-20G-A1 - Sapphire Radeon RX 470 4GB GDDR5 256-Bit HDMI / 3x DisplayPort / PCI Express 3.0 x16 Video Graphics Card
SKU: 11256-00-20G-A1
Price: $1,054.00
100322L-A1 - Sapphire Radeon HD 6450 1GB DDR3 PCI Express HDMI/ DVI Video Graphics Card
SKU: 100322L-A1
Price: $129.20
100274HDMI - Sapphire ATI Radeon HD4350 1GB DDR2 DVI/VGA/HDMI PCI Express Video Graphics Card
SKU: 100274HDMI
Price: $258.38
100256HDMI - Sapphire ATI Radeon HD4670 1GB DDR3 VGA/DVI/HDMI PCI Express Video Graphics Card
SKU: 100256HDMI
Price: $336.91
100236HDMI - Sapphire ATI Radeon HD3650 512MB DDR2 DVI/HDMI PCI Express Video Graphics Card
SKU: 100236HDMI
Price: $339.08
100294UL - Sapphire Radeon HD5550 1GB DDR2 VGA/DVI/HDMI PCI Express Video Graphics Card
SKU: 100294UL
Price: $352.07
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.