Replacement for P43357-B21: Drop-In Alternatives We Stock
Looking for a replacement for the P43357-B21 (HPE P43357-B21 ProLiant DL380 Gen10 Plus 2U Rack Server Intel Xeon Gold 5315y 3.2GHz C620a Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array P408i-a Sr Controller)? Pro Disk Network ships HP drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the P43357-B21
| SKU | P43357-B21 |
|---|---|
| Product | HPE P43357-B21 ProLiant DL380 Gen10 Plus 2U Rack Server Intel Xeon Gold 5315y 3.2GHz C620a Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array P408i-a Sr Controller |
| Current price | $11,692.63 |
| Stock status | In Stock |
| Detail page | View P43357-B21 › |
Drop-in replacements for P43357-B21
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
HPE P39882-B21 ProLiant DL360 Gen10 Plus 1U Rack-mountable Server Intel Xeon Gold 5315y 3.2GHz C621a Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array P408i-a Sr Controller
SKU: P39882-B21
Price: $7,800.00
HPE P55243-B21 ProLiant DL360 Gen10 Plus 1x Xeon Gold 5315Y 8-Core 3.20GHz 1x 32GB DDR4 8-Bays SFF MR416i-a 1x 800W PSU 1U Rack-mountable Server
SKU: P55243-B21
Price: $7,800.00
HPE P40404-B21 ProLiant DL360 Gen10 1U Rack Server Intel Xeon Gold 5222 3.8GHz C621 Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array P408i-a Controller
SKU: P40404-B21
Price: $3,073.68
HPE P40403-B21 ProLiant DL360 Gen10 2U Rack-mountable Server Intel Xeon Gold 6234 3.3GHz C621 Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array P408i-a SR Controller
SKU: P40403-B21
Price: $3,229.47
HPE P40405-B21 ProLiant DL360 Gen10 1U Rack-mountable Server Intel Xeon Gold 6248r 3.0GHz C621 Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array S100i Controller
SKU: P40405-B21
Price: $4,002.11
HPE P40399-B21 ProLiant DL360 Gen10 1U Rack-mountable Server Intel Xeon Gold 6250 3.9GHz C621 Chipset 800-Watts PS Smart Array S100i Controller
SKU: P40399-B21
Price: $4,200.00
HPE P40426-B21 ProLiant DL380 Gen10 2U Rack-mountable Server Intel Xeon Gold 6248r 3.0GHz C621 Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array S100i Sr Raid Controller
SKU: P40426-B21
Price: $4,847.37
HPE P40424-B21 ProLiant DL380 Gen10 2U Rack-mountable Server Intel Xeon Gold 6234 3.3GHz C621 Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array S100i Sr Raid Controller
SKU: P40424-B21
Price: $4,976.84
HPE P36135-B21 ProLiant DL380 Gen10 2U Rack-mountable Server Intel Xeon Gold 5218r 2.1GHz C621 Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array S100i Sr Raid Controller
SKU: P36135-B21
Price: $5,463.16
HPE P40422-B21 ProLiant DL380 Gen10 2U Rack-mountable Server Intel Xeon Gold 5222 3.8GHz C621 Chipset 32GB DDR4 SDRAM 800-Watts PS Smart Array S100i Sr Controller
SKU: P40422-B21
Price: $5,689.47
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.