Replacement for SAT5221-480G: Drop-In Alternatives We Stock
Looking for a replacement for the SAT5221-480G (Synology SAT5221-480G 480GB SATA 6Gb/s 2.5-Inch Internal Solid State Drive)? Pro Disk Network ships drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the SAT5221-480G
| SKU | SAT5221-480G |
|---|---|
| Product | Synology SAT5221-480G 480GB SATA 6Gb/s 2.5-Inch Internal Solid State Drive |
| Current price | $410.53 |
| Stock status | In Stock |
| Detail page | View SAT5221-480G › |
Drop-in replacements for SAT5221-480G
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
Kingston SKC300S37A/480G Ssdnow Kc300 480GB SATA 6GB/s 2.5-inch 7mm Internal Stand Alone Solid State Drive
SKU: SKC300S37A-480G
Price: $259.50
Kingston SV300S37A/480G Ssdnow V300 480GB SATA 6GB/s 2.5-inch Internal Stand Alone Solid State Drive
SKU: SV300S37A-480G
Price: $262.32
SEDC500R/480G Kingston Enterprise DC500R 480G 2.5 inch SATA3 Solid State Drive (TLC)
SKU: SEDC500R-480G
Price: $369.84
Kingston SUV400S37/480G SSDNow UV400 480GB 2.5 inch SATA 6GB/s Solid State Drive (TLC)
SKU: SUV400S37-480G
Price: $237.30
SDLFODAR-480G-1HA1 - SanDisk CloudSpeed Ascend 480GB SATA 6GB/s 2.5-inch Solid State Drive
SKU: SDLFODAR-480G-1HA1
Price: $274.58
SDLFGD7R-480G-1HA1 - SanDisk CloudSpeed 1000 480GB Multi-Level Cell (MLC) SATA 6Gb/s 2.5-inch Solid State Drive
SKU: SDLFGD7R-480G-1HA1
Price: $274.80
SDSSDA-480G-G26 - SanDisk 480GB SATA 6Gb/s 2.5-inch MLC Solid State Drive
SKU: SDSSDA-480G-G26
Price: $278.95
SDLFNDAR-480G-1H14 - HP 480GB Multi-Level Cell SATA 6Gb/s 2.5-inch Solid State Drive
SKU: SDLFNDAR-480G-1H14
Price: $286.32
Kingston SE50S37/480G SSDNow E50 480GB SATA 6Gb/s 2.5-inch MLC Enterprise Solid State Drive
SKU: SE50S37-480G
Price: $291.79
Kingston SA400S37/480G A400 Series 480GB Triple-Level Cell (TLC) SATA 6Gb/s 2.5-inch Solid State Drive
SKU: SA400S37-480G
Price: $291.79
SDLF1DAR-480G-1HA1 - SanDisk Cloud Speed ECO GEN II 480GB SATA 6Gb/s 2.5-inch Solid State Drive
SKU: SDLF1DAR-480G-1HA1
Price: $326.00
SDLFNDAR-480G-1HA2 - SanDisk CloudSpeed Eco 480GB Multi-Level Cell (MLC) SATA 6Gb/s 2.5-inch Solid State Drive
SKU: SDLFNDAR-480G-1HA2
Price: $369.84
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.