Replacement for R580GX4: Drop-In Alternatives We Stock
Looking for a replacement for the R580GX4 (R580GX4 - MSI AMD Radeon RX 580 4GB GDDR5 256-Bit PCI Express 3.0 x16 Video Graphics Card)? Pro Disk Network ships drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the R580GX4
| SKU | R580GX4 |
|---|---|
| Product | R580GX4 - MSI AMD Radeon RX 580 4GB GDDR5 256-Bit PCI Express 3.0 x16 Video Graphics Card |
| Stock status | In Stock |
| Detail page | View R580GX4 › |
Drop-in replacements for R580GX4
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
MSI-3602GO - MSI AMD Radeon R7 360 OC 2GB GDDR5 DVI/HDMI/DisplayPort PCI Express Video Graphics Card
SKU: MSI-3602GO
Price: $219.68
DUAL-RX580-8G - ASUS Radeon RX 580 8GB GDDR5 256-Bit 2x HDMI / 2x DisplayPort / HDCP / DVI-D PCI Express 3.0 Video Graphics Card
SKU: DUAL-RX580-8G
Price: $800.59
MSI-970GME - MSI Nvidia GeForce GTX 970 Gaming 4GB GDDR5 256-Bit 2x DVI/HDMI/DisplayPort PCI Express Video Graphics Card
SKU: MSI-970GME
Price: $996.91
MSI-970G4O - MSI Nvidia GeForce GTX 970 Gaming 4GB GDDR5 256-Bit 2x DVI/HDMI/DisplayPort PCI Express Video Graphics Card
SKU: MSI-970G4O
Price: $996.91
STRIX-R7370-DC2OC-2G - ASUS AMD Radeon R7 370 4GB GDDR5 256-Bit 2x DVI/HDMI/DisplayPort PCI Express 3.0 x16 Video Graphics Card
SKU: STRIX-R7370-DC2OC-2G
Price: $513.84
109-C20647-00 - AMD Radeon HD6990 4GB 256-Bit DVI Four Mini DisplayPorts PCI Express Video Graphics Card
SKU: 109-C20647-00
Price: $559.29
STRIX-R7370-DC2OC-4G - ASUS AMD Radeon R7 370 4GB GDDR5 256-Bit 2x DVI/HDMI/DisplayPort PCI Express 3.0 x16 Video Graphics Card
SKU: STRIX-R7370-DC2OC-4G
Price: $918.49
R9270X-DC2T-4GD5 - ASUS AMD Radeon R9 270X 4GB GDDR5 256-Bit PCI Express 3.0 x16 Video Graphics Card
SKU: R9270X-DC2T-4GD5
Price: $962.05
9WR6Y - Dell AMD Radeon R9 M290X 4GB 256-Bit GDDR5 PCI Express 3 x16 4096 x 2160 Graphics Card for Alienware 17 R1 / 18 R1
SKU: 9WR6Y
Price: $977.88
08DG8P - Dell / AMD Radeon HD 7970M 4GB GDDR5 256-Bit PCI-Express 3 x16 MXM 3 ATI X Video Graphics Card
SKU: 08DG8P
Price: $977.88
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.