Replacement for P24253-B21: Drop-In Alternatives We Stock
Looking for a replacement for the P24253-B21 (HPE P24253-B21 InfiniBand MCX653105A-HDR/Ethernet 1-Port 200GbE QSFP56 PCIe4 x16 Network Adapter)? Pro Disk Network ships HP drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the P24253-B21
| SKU | P24253-B21 |
|---|---|
| Product | HPE P24253-B21 InfiniBand MCX653105A-HDR/Ethernet 1-Port 200GbE QSFP56 PCIe4 x16 Network Adapter |
| Current price | $1,570.53 |
| Stock status | In Stock |
| Detail page | View P24253-B21 › |
Drop-in replacements for P24253-B21
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
HPE P24753-001 HP P24753-001 InfiniBand MCX653105A-HDR/Ethernet 1-Port 200GbE QSFP56 PCIe4 x16 Network Adapter
SKU: P24753-001
Price: $797.89
HPE P23664-B21 Infiniband Hdr/Ethernet 1-Port 200GbE QSFP56 PCI Express 4.0 x16 Network Adapter for ProLiant Dl Rackmount Gen10 Plus Servers
SKU: P23664-B21
Price: $1,570.53
HPE P24247-001 HP P24247-001 InfiniBand MCX653105A-HDR/Ethernet 1-Port 200GbE QSFP56 PCIe4 x16 Network Adapter
SKU: P24247-001
Price: $1,570.53
HPE P24250-001 HP P24250-001 InfiniBand MCX653105A-HDR/Ethernet 1-Port 200GbE QSFP56 PCIe4 x16 Network Adapter
SKU: P24250-001
Price: $1,570.53
HPE P23664-H21 1x Port 200GbE QSFP56 HDR/Ethernet PCI Express 4.0 x16 InfiniBand Network Adapter
SKU: P23664-H21
Price: $1,570.53
HPE R7R46A HP R7R46A InfiniBand MCX653105A-HDR/Ethernet 1-Port 200GbE QSFP56 PCIe4 x16 Network Adapter
SKU: R7R46A
Price: $1,570.53
HPE P10774-B21 HP P10774-B21 Mellanox InfiniBand HDR 40-Ports QSFP56 UnManageable Back to Front Airflow 1U Rack-mountable Layer 2 Gigabit Ethernet Network Switch
SKU: P10774-B21
Price: $5,776.84
HPE R7R45A InfiniBand HDR/100 2-Ports 100Gb/s QSFP28 PCI Express 4.0 x16 Network Adapter
SKU: R7R45A
Price: $629.47
HPE P08355-001 InfiniBand HDR100/Ethernet 2-Ports 100GbEPCI-Express 3.0 x16 Low-Profile Gigabit Ethernet Network Adapter
SKU: P08355-001
Price: $549.47
HPE 828108-001 InfiniBand EDR / Ethernet 1-Port 100Gb/s 840QSFP28 Network Adapter
SKU: 828108-001
Price: $268.42
HPE P24754-001 InfiniBand MCX653105A-ECAT HDR100/Ethernet 100GbE 1-Port QSFP56 PCIe4 x16 Network Adapter
SKU: P24754-001
Price: $534.74
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.