Replacement for OS8381: Drop-In Alternatives We Stock
Looking for a replacement for the OS8381 (OS8381 - HP 2.50GHz 6MB L3 Cache AMD Opteron 8381 HE Quad Core Processor)? Pro Disk Network ships HP drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the OS8381
| SKU | OS8381 |
|---|---|
| Product | OS8381 - HP 2.50GHz 6MB L3 Cache AMD Opteron 8381 HE Quad Core Processor |
| Current price | $96.84 |
| Stock status | In Stock |
| Detail page | View OS8381 › |
Drop-in replacements for OS8381
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
535708-001 - HP 2.5GHz 6MB L3 Cache AMD Opteron 8381 HE Quad Core Processor
SKU: 535708-001
Price: $96.84
530531-002 - HP 2.50GHz 2000MHz HTL 6MB L3 Cache Socket Fr5(1207) AMD Opteron 8381 HE Quad Core Processor
SKU: 530531-002
Price: $192.97
535677-L21 - HP 2.5GHz 2000MHz HTL 6MB L3 Cache Socket Fr5(1207) AMD Opteron 8381 HE Quad Core Processor
SKU: 535677-L21
Price: $212.29
534508-L21 - HP 2.5GHz 2000MHz FSB 6MB L3 Cache Socket F(1207) AMD Opteron 8381 HE Quad-Core Processor
SKU: 534508-L21
Price: $215.79
508864-L21 - HP 2.5GHz 2000MHz FSB 6MB L3 Cache Socket F(1207) AMD Opteron 8381 HE Quad-Core Processor
SKU: 508864-L21
Price: $215.79
534508-B21 - HP 2.5GHz 2000MHz FSB 6MB L3 Cache Socket F(1207) AMD Opteron 8381 HE Quad-Core Processor
SKU: 534508-B21
Price: $236.84
536577-B21 - HP 2.50GHz 6MB L3 Cache AMD Opteron 8381 HE Quad Core Processor Kit
SKU: 536577-B21
Price: $265.26
535677-B21 - HP 2.50GHz 6MB L3 Cache AMD Opteron 8381 HE Quad Core Processor
SKU: 535677-B21
Price: $366.32
508864-B21 - HP 2.50GHz 6MB L3 Cache Socket Fr5(1207) AMD Opteron 8381 HE 4-Core Processor
SKU: 508864-B21
Price: $215.79
500517-001 - HP AMD Opteron 8380 Quad Core 2.5GHz 2MB L2 Cache 6MB L3 Cache 1000MHz Socket-F 1207 75W Processor Kit for Proliant DL585 G5 Server
SKU: 500517-001
Price: $184.21
507528-B21 - HP AMD Opteron 8380 Quad Core 2.5GHz 2MB L2 Cache 6MB L3 Cache 1000MHz FSB Socket-Processor
SKU: 507528-B21
Price: $1,044.21
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.