Replacement for 11221-00-20G: Drop-In Alternatives We Stock
Looking for a replacement for the 11221-00-20G (11221-00-20G - Sapphire AMD Radeon R9 280X 3GB GDDR5 384-Bit PCI Express 3.0 x16 Video Graphics Card)? Pro Disk Network ships drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the 11221-00-20G
| SKU | 11221-00-20G |
|---|---|
| Product | 11221-00-20G - Sapphire AMD Radeon R9 280X 3GB GDDR5 384-Bit PCI Express 3.0 x16 Video Graphics Card |
| Current price | $815.97 |
| Stock status | In Stock |
| Detail page | View 11221-00-20G › |
Drop-in replacements for 11221-00-20G
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
11215-00-20G - Sapphire Radeon R7 250 1GB GDDR5 VGA/ DVI/ HDMI PCI Express Video Graphics Card
SKU: 11215-00-20G
Price: $524.88
11202-00-20G - Sapphire Radeon HD 7750 1GB DDR5 PCI Express Video Graphics Card
SKU: 11202-00-20G
Price: $526.97
11200-06-20G - Sapphire Radeon HD 7850 Overclocked 1GB PCI Express DVI Video Graphics Card
SKU: 11200-06-20G
Price: $576.18
11216-00-20G - Sapphire Radeon R7 240 2GB DDR3 128-Bit HDMI/ DVI-D PCI Express 3.0 x16 Low Profile Video Graphics Card
SKU: 11216-00-20G
Price: $579.74
11229-00-20G - Sapphire Radeon R7 250x 1GB GDDR5 128-Bit Dual-Link DVI-I/ HDMI/ DisplayPort PCI Express 3.0 x16 Video Graphics Card
SKU: 11229-00-20G
Price: $641.88
11200-00-20G - Sapphire Radeon HD 7850 2GB 256-Bit GDDR5 PCI Express 3.0 x16 HDMI/DVI/2x Mini DisplayPort Video Graphics Card
SKU: 11200-00-20G
Price: $667.43
11232-00-20G - Sapphire Radeon R7 265 2GB GDDR5 DVI-I / DVI-D / HDMI / DP Dual-X PCI-Express Graphics Card
SKU: 11232-00-20G
Price: $673.51
11217-00-20G - Sapphire Vapor-X Radeon R9 270X OC 2GB DDR5 Dual DVI/ HDMI/ DisplayPort PCI Express Video Graphics Card
SKU: 11217-00-20G
Price: $683.30
11200-16-20G - Sapphire Radeon HD 7850 1GB GDDR5 PCI Express 2DVI/ HDMI/DisplayPort Video Graphics Card
SKU: 11200-16-20G
Price: $724.72
11200-14-20G - Sapphire Radeon HD 7850 2GB OC GDDR5 PCI Express 3.0 x16 Video Graphics Card
SKU: 11200-14-20G
Price: $781.21
11200-01-20G - Sapphire Radeon HD 7850 OC 2GB 256-Bit DDR5 Express 3.0 x16 HDMI/DVI HDCP Ready CrossFireX Support Video Graphics Card
SKU: 11200-01-20G
Price: $887.32
21260-00-20G - Sapphire Radeon RX 480 8GB GDDR5 PCI Express 3.0 Video Graphics Card
SKU: 21260-00-20G
Price: $996.91
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.