$1,861.30In Stock — Usually Ships in 1–3 Business Days
About the HX-CPU-E52680E
This Cisco HX-CPU-E52680E delivers Intel Unboxed Processors functionality and is built for 24/7 enterprise duty cycles. Technical specifications include clock speed of 2.40 GHz, bus speed of 9.6 GT/s, cache of Intel Smart Cache, socket of FCLGA2011. Common deployment scenarios include in-place server upgrades from prior Xeon/EPYC generations, matched-pair second-socket installation, hot-spare provisioning, and refurbished rebuild programs for older platforms. Pro Disk Network maintains the HX-CPU-E52680E in our enterprise inventory and verifies each unit against manufacturer datasheet specifications prior to listing. New stock ships factory-sealed where available; refurbished units are tested under load before dispatch and ship with a 90-day Pro Disk Network functional warranty. Dispatch in 1–3 business days; free standard ground shipping on US orders over $150.
The HX-CPU-E52680E is a Cisco intel unboxed processors component with clock speed 2.40 GHz, bus speed 9.6 GT/s, cache Intel Smart Cache. Pro Disk Network sells the HX-CPU-E52680E for $1,861.30 with US shipping in 1–3 business days and a 30-day return guarantee.
Reviewed By
Reviewed by:Pro Disk Network Engineering Team — . Specifications, compatibility, and pricing for the HX-CPU-E52680E are shown on this page.
Trust Signals
US-based LLC — 7345 W Sand Lake Rd, STE 210, Office 3208, Orlando, FL 32819
US Shipping in 1–3 Business Days — in-stock orders ship via UPS
30-Day Returns — pre-paid label on DOA and defective items
Quick Answer: What socket does the HX-CPU-E52680E use?
Confirm the socket against your motherboard's CPU support list - Intel Xeon Scalable spans LGA 3647 (1st/2nd gen), LGA 4189 (3rd gen Ice Lake), and LGA 4677 (4th/5th gen Sapphire/Emerald Rapids). A BIOS update is often required for newer steppings even on the same socket. Email sales@prodisknetwork.com with your motherboard model for a compatibility check.
How fast does the HX-CPU-E52680E ship?
If in stock, the HX-CPU-E52680E ships in 1–3 business days. Most US ZIP codes receive next-business-day or 2-day delivery via FedEx/UPS Ground or Express. Bulk and pallet orders may need extra handling time; we confirm the ship date with your order.
The HX-CPU-E52680E is deployed by US enterprises, MSPs, government, and education customers across multiple infrastructure scenarios. Below are the most common deployment patterns Pro Disk Network sees in real-world orders.
VMware vSphere ESXi 8 Host — Per-CPU core count drives VVF/VCF licensing cost — choose 16–24 cores for cost-optimal density unless workload is core-bound.
Hyper-V Cluster Node — Windows Server Datacenter licenses by core, but Hyper-V scales linearly. Higher-clock, mid-core SKUs win for transactional workloads.
Citrix VDI Pool — Frequency-sensitive — prefer high-clock 16–18 core SKUs over high-core-count parts to maintain user-perceived snappiness.
Kubernetes / Tanzu Workers — Higher core count amortises better across many small Pods. EVC mode planning matters for live-migrate parity.
What is the HX-CPU-E52680E?
The HX-CPU-E52680E is a Cisco server-class processor with clock speed 2.40 GHz and bus speed 9.6 GT/s, manufactured by Cisco. Pro Disk Network ships this part new and certified-refurbished from our US warehouse with dispatch in 1–3 business days, backed by a 30-day return guarantee.
Pros & Cons of HX-CPU-E52680E
Pros
Shipping in 1–3 business days from our US warehouse cuts deployment lead time
Cons
Older microarchitecture — not appropriate for new AI/AMX workloads
Not always silicon-binned for overclocking
Stepping mismatch with newer revisions can require microcode update
Frequently Asked Questions about HX-CPU-E52680E
Is the HX-CPU-E52680E a genuine Cisco part?
Yes. Pro Disk Network sources every HX-CPU-E52680E as factory-original Cisco inventory. New units arrive sealed in OEM packaging; refurbished units are pulled from decommissioned Cisco servers, surface-tested, and re-warranted by Pro Disk Network for 90 days.
What socket does the HX-CPU-E52680E use?
Confirm the socket against your motherboard's CPU support list - Intel Xeon Scalable spans LGA 3647 (1st/2nd gen), LGA 4189 (3rd gen Ice Lake), and LGA 4677 (4th/5th gen Sapphire/Emerald Rapids). A BIOS update is often required for newer steppings even on the same socket. Email sales@prodisknetwork.com with your motherboard model for a compatibility check.
How fast does the HX-CPU-E52680E ship?
If in stock, the HX-CPU-E52680E ships in 1–3 business days. Most US ZIP codes receive next-business-day or 2-day delivery via FedEx/UPS Ground or Express. Bulk and pallet orders may need extra handling time; we confirm the ship date with your order.
What is the warranty on the HX-CPU-E52680E?
New HX-CPU-E52680E units carry the full Cisco manufacturer warranty (typically 1 to 5 years depending on product line). Refurbished and bulk-OEM units include a Pro Disk Network advance-replacement warranty (90 days refurbished). DOA replacement is free within 30 days of receipt.
Do you offer bulk pricing for the HX-CPU-E52680E?
Email sales@prodisknetwork.com with the quantity and target ship date for a quote within one business day.
Pro Disk Network Buyer’s Guide: Intel Unboxed Processors
Socket Compatibility, EVC Mode, and BIOS Revision Planning
Choosing the HX-CPU-E52680E for a server upgrade or replacement starts with socket compatibility. CPU sockets are tied to motherboard chipsets and revisions; a board that supports Skylake-SP may or may not support Cascade Lake-SP depending on BIOS. Before ordering, look up the motherboard QVL (qualified vendor list) and confirm the HX-CPU-E52680E appears with a supported BIOS version. If the BIOS needs an update, plan the flash before swapping CPUs — many systems will not POST long enough to flash with the wrong CPU installed.
AI Workloads, AMX, and the Inference Performance Story
For dedicated AI inference hosts, prioritize core count over clock speed. INT8 inference is bandwidth-bound, not frequency-bound, so a 32-core part at 2.5 GHz outperforms a 16-core part at 3.5 GHz on most LLM workloads. For mixed virtualisation + occasional inference workloads, prioritize clock speed — VDI and OLTP database workloads benefit from the higher frequency.