Replacement for M5A78L-M-Plus-USB-3: Drop-In Alternatives We Stock
Looking for a replacement for the M5A78L-M-Plus-USB-3 (Asus M5A78L-M Plus/USB 3 M5A78L-M PLUS/USB3 Desktop Motherboard AMD 760G Chipset)? Pro Disk Network ships drop-in replacements and equivalent modern parts from US inventory. Every alternate below is in-stock today with same-day shipping for orders placed before 2pm ET. If your unit is still under warranty, contact our engineering team — we offer cross-shipping for B2B customers on Net 30 terms.
About the M5A78L-M-Plus-USB-3
| SKU | M5A78L-M-Plus-USB-3 |
|---|---|
| Product | Asus M5A78L-M Plus/USB 3 M5A78L-M PLUS/USB3 Desktop Motherboard AMD 760G Chipset |
| Stock status | In Stock |
| Detail page | View M5A78L-M-Plus-USB-3 › |
Drop-in replacements for M5A78L-M-Plus-USB-3
Each part below is currently in our US warehouse, ships same-day for orders before 2pm ET, and includes our 90-day warranty. SKUs link to the full product page with photos, datasheets and B2B quote form.
90-MIBB70-G0EAY00Z - ASUS Asus M4A78L-M Motherboard AM2+ AMD 760G mATX RAID SATA Gigabit L
SKU: 90-MIBB70-G0EAY00Z
Price: $222.93
M5A78L-MLXPLUS-BO-R - ASUS M5a78l-m Lx Plus Amd 760g Socket Am3+ Matx Motherboard W/vi
SKU: M5A78L-MLXPLUS-BO-R
Price: $245.25
F5U407TT - Belkin 4 Port USB 2.0 Ultra Mini Hub - 4 x USB 2.0 USB Downstream 1 x USB 2.0 USB Upstream - External
SKU: F5U407TT
Price: $128.95
F5U404TTBLK - Belkin F5U404TTBLK 4-port USB Hub - 4 x 4-pin Type A USB 2.0 USB 1 x USB 2.0 USB - External
SKU: F5U404TTBLK
Price: $146.55
F5U220 - Belkin USB 2.0 5-Port PCI Card - 4 x 4-pin Type A USB 2.0 USB External 1 x 4-pin Type A USB 2.0 USB Internal - Plug-in Card
SKU: F5U220
Price: $189.47
F5U220V1 - Belkin Hi-Speed USB 2.0 5-Port PCI Card - 4 x 4-pin Type A USB 2.0 USB External 1 x 4-pin Type A USB 2.0 USB Internal - Plug-in Card
SKU: F5U220V1
Price: $285.17
90-MIBBJ0-G0EAY00Z - ASUS M4A78LT-M AMD 760G Phenom II/Athlon II/Sempron 100 Series Processors Support Socket AM3 micro-ATX Motherboard
SKU: 90-MIBBJ0-G0EAY00Z
Price: $206.05
AS04M4A78LT01 - ASUS M4a78lt-m Le AMD 760g Am3 DDR3 Radeon 3000 PCI Express Gb Matx Motherboard
SKU: AS04M4A78LT01
Price: $275.36
Asus M5A78L-M/USB3 AMD 760G / SB710 DDR3 4-Slot System Board (Motherboard) Socket AM3+
SKU: M5A78L-M-USB3
Price: $344.84
90-MIBB90-G0EAY00Z - ASUS M4A78LT-M LE / AMD 760G / Sockel AM3 Mainboard
SKU: 90-MIBB90-G0EAY00Z
Price: $279.41
ASUS A55M-A/USB3-DDO A55m-a/usb3 Fm2 Amd A55 Hudson D2 HDmi Usb 3.0 Uatx Usb 3 Motherboard
SKU: A55M-A-USB3-DDO
Price: $332.84
How we pick replacements
Every recommendation above was selected using these criteria:
- Drop-in compatibility — same form factor (2.5"/3.5", PCIe slot, SFP port, etc.), so it fits the original chassis without modification
- Equivalent or better performance — matched on RPM/IOPS/speed/throughput, never downgraded
- Same-brand-preferred — we list the OEM-equivalent first when available, then trusted aftermarket
- Warranty coverage — 90-day Pro Disk warranty on every part, with 1-year option for B2B
- In stock today — never recommend a part that is on backorder
Need help confirming compatibility?
Our engineers validate every replacement against your specific server, switch, or chassis model before shipment. Email sales@prodisknetwork.com with your platform model (e.g., Dell PowerEdge R740, HP DL380 Gen10, Cisco Catalyst 9300) and we will confirm the exact part number that drops into your hardware.